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. 2023 Oct 11;12(10):1532. doi: 10.3390/antibiotics12101532

Figure 8.

Figure 8

Determining the antimicrobial activity of modified CLEC3A-derived peptide dWRK-30. (a) Antimicrobial activity assay using LL-37 (* p = 0.020), DK-29, WRK-30, and dWRK-30 in P. aeruginosa. The bar chart shows the determined MIC50 of the peptides. (b) Antimicrobial activity assay using LL-37, DK-29, WRK-30, and dWRK-30 in S. aureus. The bar chart shows the determined MIC50 of the peptides. (c) Antimicrobial activity assay using LL-37 (* p = 0.024), DK-29, WRK-30, and dWRK-30 (* p = 0.027) in MRSA. The bar chart shows the determined MIC50 of the peptides including the numerical values with confidence intervals as legend. Depicted are averages and standard deviations. Statistical significance was calculated using Prism 9 with a paired ANOVA test followed by a Dunett test and multiple comparisons, comparing each peptide with WRK-30. All experiments were repeated three times (n = 3).