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. 2023 Sep 24;13(10):1440. doi: 10.3390/biom13101440

Table 1.

Demographic, sleep recording variables, and laboratory findings of the groups.

Variables AHI Groups p
Control
AHI < 5 (n:46)
Mild OSAS
(5 < AHI < 15) (n:14)
Moderate OSAS (15 < AHI < 30)
(n:23)
Severe OSAS
(AHI > 30)
(n:88)
Age (Year) 41.67 ± 11.04 a 49.92 ± 11.25 ab 48.55 ± 13.97 ab 52.57 ± 10.62 b <0.001 *
Height (m) 170.13 ± 9.84 165.00 ± 9.58 167.09 ± 10.23 167.93 ± 7.95 0.228 *
Weight (kg) 74.61 ± 13.91 a 80.50 ± 8.28 ac 91.13 ± 19.20 bc 93.55 ± 16.37 b <0.001 *
BMI ( kg/m2) 25.66 ± 3.59 a 29.76 ± 4.17 ac 32.91 ± 8.11 bc 33.34 ± 6.52 bc <0.001 *
 MOS (%) 93.00 (90.00–96.75) a 90.00 (85.00–90.00) a 81.00 (75.00–87.00) ab 76.00 (66.25–83.00) b <0.001
SpO2 (%) 95.50 (92.00–97.00) 94.50 (91.00–95.25) 93.00 (91.00–94.00) 92.00 (90.00–94.00) 0.083 ¶
Irisin (µg/mL) 3.20 ± 0.79 a 3.52 ± 0.67 a 2.96 ± 0.23 a 2.34 ± 0.76 b <0.001 *
RBP-4 (ng/mL) 28.00 ± 9.58 a 34.64 ± 5.96 ab 42.81 ± 11.72 b 51.24 ± 11.13 c <0.001 *
Adiponectin (µg/mL) 8.74 (7.58–10.57) a 6.34 (5.73–7.40) b 5.99 (5.49–7.94) b 6.67 (5.43–8.92) b <0.001
Gender n (%) n (%) n (%) n(%)
 Female 15 (32.6) 6 (42.9) 7 (30.4) 21 (23.9) 0.431 †
 Male 31 (67.4) 8 (57.1) 16 (69.6) 67 (76.1)
Obesity
No 22 (47.8) 8 (57.1) 8 (34.8) 28 (31.8) 0.137 †
Yes 24 (52.2) 6 (42.9) 15 (65.2) 60 (68.2)
DM
No 46 (100.0) a 13 (100.0) ab 21 (91.3) ab 69 (78.4) b 0.001 ●
Yes 0 (0.0) a 0 (0.0) ab 2 (8.7) ab 19 (21.6) b
HT
No 45 (97.8) a 10 (76.9) b 11 (47.8) b 49 (56.3) b <0.001 ●
Yes 1 (2.2) a 3 (23.1) b 12 (52.2) b 38 (43.7) b

AHI, apnea hypopnea ındex; MOS, minimum oxygen saturation; SpO2: oxygen saturation calculated through pulse oxymeter; RBP-4, retinol binding protein; DM, diabetes mellitus; HT, hypertension. Values are shown as mean ± standard deviation or median (1 st quarter–3 rd quarter) and n (%). p < 0.05 values are shown in bold. Different superscript letters indicate groups with significant differences. *: One-way ANOVA was applied; ¶: Kruskal–Wallis test was applied; †: Chi-square test was applied; ●: Fishers exact test was applied.