Table 2.
Demographic and clinical characteristics of the training and internal validation sets
| Variables | Total (N = 17,667) | Training set (N = 12,366) | Internal validation set (N = 5,301) | P values |
|---|---|---|---|---|
| Age(IQR, year) | 73.00(68.00,78.00) | 73.00(68.00,78.00) | 73.00(68.00,78.00) | 0.795 |
| Sex(n, %) | 0.426 | |||
| Female | 9529 | 6694 | 2835 | |
| Male | 8138 | 5672 | 2466 | |
| Hypertension(n, %) | 0.177 | |||
| No | 7470 | 5188 | 2282 | |
| Yes | 10,197 | 7178 | 3019 | |
| CHD(n, %) | 0.593 | |||
| No | 12,796 | 8942 | 3854 | |
| Yes | 4871 | 3424 | 1447 | |
| CI(n, %) | 0.267 | |||
| No | 14,609 | 10,200 | 4409 | |
| Yes | 3058 | 2166 | 892 | |
| Hyperlipidemia(n, %) | 0.889 | |||
| No | 15,251 | 10,672 | 4579 | |
| Yes | 2416 | 1694 | 722 | |
| PSH(n, %) | 0.673 | |||
| No | 8519 | 5950 | 2569 | |
| Yes | 9148 | 6416 | 2732 | |
| PMH(n, %) | 0.417 | |||
| No | 1813 | 1254 | 559 | |
| Yes | 15,854 | 11,112 | 4742 | |
| Amoking history(n, %) | 0.278 | |||
| No | 12,879 | 9044 | 3835 | |
| Yes | 4788 | 3322 | 1466 | |
| Srinking history(n, %) | 0.089 | |||
| No | 13,761 | 9675 | 4086 | |
| Yes | 3906 | 2691 | 1215 | |
| SBP(IQR, mmHg) | 139.00(126.00,153.00) | 139.00(126.00,154.00) | 139.00(126.00,153.00) | 0.301 |
| DBP(IQR, mmHg) | 78.00(70.00,86.00) | 78.00(70.00,85.00) | 78.00(70.00,86.00) | 0.586 |
| pulse(IQR, bpm) | 80.00(72.00,89.00) | 80.00(72.00,89.00) | 80.00(72.00,90.00) | 0.330 |
| AST(IQR, IU/L) | 20.00(16.00,27.00) | 20.00(16.00,27.00) | 20.00(16.00,27.00) | 0.311 |
| ALT(IQR, IU/L) | 18.00(13.00,26.60) | 18.00(13.00,27.00) | 18.00(13.00,26.00) | 0.541 |
| TGs(IQR, mmol/l) | 1.42(1.04,2.03) | 1.43(1.04,2.02) | 1.41(1.05,2.04) | 0.765 |
| NLR(IQR) | 3.17(2.14,5.23) | 3.17(2.14,5.25) | 3.18(2.14,5.16) | 0.988 |
| PLR(IQR) | 126.63(92.73,178.67) | 126.84(92.79,179.39) | 126.05(92.51,176.98) | 0.687 |
| LMR(IQR) | 3.84(2.54,5.49) | 3.85(2.54,5.45) | 3.84(2.55,5.57) | 0.833 |
| NPAR(IQR, ml/g) | 17.31(14.96,20.47) | 17.35(14.96,20.52) | 17.23(14.96,20.37) | 0.396 |
| CREA(IQR, umol/l) | 70.40(57.00,90.00) | 70.30(57.00,90.20) | 70.40(56.90,89.40) | 0.372 |
| UA(IQR, umol/l) | 320.00(256.90,396.90) | 321.05(257.50,397.48) | 317.30(255.00,395.30) | 0.106 |
| LDL-C(IQR, mmol/l) | 2.42(1.86,3.05) | 2.42(1.86,3.04) | 2.42(1.87,3.06) | 0.896 |
| HDL-C(IQR, mmol/l) | 1.12(0.93,1.35) | 1.12(0.93,1.35) | 1.13(0.93,1.35) | 0.479 |
| HbA1c(IQR, %) | 7.69(6.65,9.90) | 7.70(6.6125,9.85) | 7.69(6.70,10.00) | 0.503 |
| GFR(IQR, mL/min) | 85.60(65.43,102.41) | 85.51(65.12,102.45) | 85.87(65.96,102.31) | 0.392 |
CHD: coronary heart disease; CI: cerebral infarction; PSH: past surgical history; PMH: past medical history ; SBP: systolic blood pressure; DBP: diastolic blood pressure; AST:aspartate aminotransferase; ALT: alanine aminotransferase; TGs: triglycerides; NLR: neutrophil-to-lymphocyte ratio; PLR: platelet-to-lymphocyte ratio; LMR: lymphocyte to monocyte ratio; NPAR: neutrophil percentage-to-albumin ratio; CREA: creatinine; UA: uric acid; LDL-C: low density lipoprotein cholesterol; HDL-C: high density lipoprotein cholesterol; HbA1c: glycated hemoglobin; GFR: glomerular filtration rate; IQR: interquartile range