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. 2023 Sep 25;13(10):1443. doi: 10.3390/biom13101443

Table 1.

List of genes and enzymes involved in the nitrogen cycle.

No. KEGG ID Gene Symbol Gene Name EC Number Reference
1 K04561 NORB Nitric oxide reductase subunit B 1.7.2.5 [125,126]
2 K15877 CYP55 Fungal nitric oxide reductase 1.7.1.14 [131,132]
3 K00376 NOSZ Nitrous-oxide reductase 1.7.2.4 [133,134,135]
4 K02586 NIFD Nitrogenase molybdenum-iron protein alpha chain 1.18.6.1 [136]
5 K22896 VNFD Vanadium-dependent nitrogenase alpha chain 1.18.6.2 [137]
6 R05186 NIFF Nitrogenase 1.19.6.1 [138]
7 K01455 FORMAMIDASE Formamidase 3.5.1.49 [139]
8 K20935 HDH Hydrazine dehydrogenase 1.7.2.8 [140]
9 K20932 K20932 Hydrazine synthase subunit 1.7.2.7 [141]
10 K01672 CA Carbonic anhydrase 4.2.1.1 [142,143]
11 K01725 CYNS Cyanate lyase 4.2.1.104 [144]
12 K00368 NIRK Nitrite reductase (NO-forming) 1.7.2.1 [145]
13 K02575 NRT2, NARK, NRTP, NASA MFS transporter, NNP family, nitrate/nitrite transporter ------ [146]
14 K15576 NRTA, NRTB, NRTC, NASD Nitrate/nitrite transport system substrate-binding protein 7.3.2.4 [147]
15 K00370 NARG, NARZ, NXRA Nitrate reductase/nitrite oxidoreductase, alpha subunit 1.7.5.1
1.7.99.-
[148]
16 K10534 NR Nitrate reductase (NAD(P)H) 1.7.1.1 1.7.1.2 1.7.1.3 [149]
17 K00367 NARB Ferredoxin-nitrate reductase 1.7.7.2 [150]
18 K02567 NAPA Nitrate reductase (cytochrome) 1.9.6.1 [130]
19 K17877 NIT-6 Nitrite reductase (NAD(P)H) 1.7.1.4 [128]
20 K00366 NIRA Ferredoxin-nitrite reductase 1.7.7.1 [151]
21 K00362 NIRB Nitrite reductase (NADH) large subunit 1.7.1.15 [152]
22 K03385 NRFA Nitrite reductase (cytochrome c-552) 1.7.2.2 [153]
23 K00459 NCD2, NPD Nitronate monooxygenase 1.13.12.16 [154]
24 K19823 NAO Nitroalkane oxidase 1.7.3.1 [155]
25 R00143 Hydroxylamine reductase (NADH) 1.7.1.10 [156]
26 K05601 HCP Hydroxylamine reductase 1.7.99.1 [157]
27 K10535 HAO Hydroxylamine dehydrogenase 1.7.2.6 [157]
28 R10230 Hydroxylamine oxidase (cytochrome) 1.7.3.6 [158]
29 K10944 PMOA-AMOA Methane/ammonia monooxygenase subunit A 1.14.18.3 1.14.99.39 [159]
30 K00926 ARCC Carbamate kinase 2.7.2.2 [160]
31 K01948 CPS1 Carbamoyl-phosphate synthase (ammonia) 6.3.4.16 [161]
32 K00260 GUDB, ROCG Glutamate dehydrogenase 1.4.1.2 [162]
33 K00261 GLUD1_2, GDHA Glutamate dehydrogenase (NAD(P)+) 1.4.1.3 [163]
34 K00262 E1.4.1.4, GDHA Glutamate dehydrogenase (NADP+) 1.4.1.4 [164]
35 K01915 GLNA, GLUL Glutamine synthetase 6.3.1.2 [165]
36 K01501 E3.5.5.1 Nitrilase 3.5.5.1 [166]
37 K00265 GLTB Glutamate synthase (NADPH) large chain 1.4.1.13 [167]
38 K00264 GLT1 Glutamate synthase (NADH) 1.4.1.14 [168]
39 K00284 GLU, GLTS Glutamate synthase (ferredoxin) 1.4.7.1 [169]
40 K00372 NASC, NASA Assimilatory nitrate reductase catalytic subunit 1.7.99.- [127]
41 K26139 NASD, NASB Nitrite reductase [NAD(P)H] large subunit 1.7.1.4 [127]
42 K15864 NIRS Nitrite reductase (NO-forming)/hydroxylamine reductase 1.7.2.1 1.7.99.1 [170,171]
43 K00531 ANFG Nitrogenase delta subunit 1.18.6.1 [120]
44 K04561 NORB Nitric oxide reductase subunit B 1.7.2.5 [125,126]