Figure 1.

(A) Treatment/testing paradigm of the study. The mice received a daily STZ i.p. injection for five consecutive days. Three days after the last STZ injection, glycemic levels were measured; the animals were assigned to different experimental groups, and the protocol of Lipo, LG, or LipoLG administration begun. ERG recordings (red line) were performed after 6 weeks from the last STZ injection. After the ERG recordings, the mice were sacrificed and their retinas were used for Western blot analyses. The glycemia and the body weight of the mice during the experimental period are shown in (B,C), respectively. The dashed line in (B) indicates glycemia = 250 mg/dL. n = 4 in all graphs.