Table 4.
Univariate model performance for overall, PZ-based, and TZ-based analyses.
| Features | Sensitivity (% ± SD) |
Specificity (% ± SD) |
PPV (% ± SD) |
NPV (% ± SD) |
Accuracy (%) |
|---|---|---|---|---|---|
| Peripheral and transitional zone | |||||
| PSA density | 49 ± 12 | 91 ± 11 | 93 ± 8 | 43 ± 7 | 61 |
| T2-wavelet-HHH_glszm_GrayLevelVariance | 74 ± 14 | 52 ± 20 | 80 ± 7 | 47 ± 17 | 68 |
| T2-wavelet-LLL_glszm_GrayLevelVariance | 64 ± 11 | 63 ± 19 | 82 ± 8 | 42 ± 10 | 64 |
| ADC-original_glcm_ClusterShade | 81 ± 10 | 62 ± 18 | 84 ± 7 | 58 ± 16 | 76 |
| ADC-wavelet-HHH_firstorder_Minimum | 31 ± 30 | 71 ± 22 | 44 ± 37 | 31 ± 10 | 42 |
| ADC-wavelet-LLL_glrlm_LongRunHighGrayLevelEmphasis | 49 ± 23 | 57 ± 30 | 77 ± 13 | 31 ± 11 | 51 |
| Peripheral zone | |||||
| PSA density | 46 ± 14 | 89 ± 18 | 94 ± 10 | 36 ± 9 | 57 |
| T2-wavelet-HHH_glszm_GrayLevelVariance | 70 ± 15 | 57 ± 25 | 83 ± 9 | 41 ± 17 | 67 |
| T2-wavelet-HHH_glszm_LowGrayLevelZoneEmphasis | 64 ± 17 | 61 ± 25 | 84 ± 9 | 38 ± 15 | 63 |
| T2-wavelet-LLL_glszm_GrayLevelVariance | 67 ± 12 | 81 ± 18 | 92 ± 8 | 47 ± 12 | 70 |
| ADC-original_glrlm_ShortRunHighGrayLevelEmphasis | 72 ± 12 | 68 ± 24 | 87 ± 8 | 46 ± 15 | 71 |
| ADC-wavelet-LLL_gldm_HighGrayLevelEmphasis | 82 ± 14 | 51 ± 23 | 83 ± 7 | 54 ± 24 | 74 |
| Transition zone | |||||
| ADC-wavelet-LLL_glcm_ClusterShade | 80 ± 23 | 70 ± 30 | 82 ± 19 | 74 ± 29 | 76 |
ADC: apparent diffusion coefficient; NPV: negative predictive value; PPV: positive predictive value; PSA: prostate-specific antigen; SD: standard deviation.