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Increased activation of mitogen-activated protein kinase (MAPK) p38 in fibrinogen-adhered PP1cα−/− platelets. (A) Washed platelets were maintained in suspension over bovine serum albumin (BSA) or allowed to adhere to fibrinogen (FGN). Lysate was immunoblotted with anti-phospho Thr180, Tyr182 p38, and anti-p38 antibodies. (B) Densitometry quantification of three independent experiments. * p < 0.05.
