Table 1.
Current therapeutic treatments and emerging therapies to cure NASH
| Current therapies | |
| Lifestyle changes | Increased physical activity |
| Specified dietary restrictions | |
| Insulin-sensitizing agents | Metformin |
| Pioglitazone | |
| Antioxidant agent | α-tocopherol (vitamin E) |
| Lipid-lowering drugs | Statins |
| Emerging therapies | |
| Anti-inflammatory and/or antifibrotic treatments | Resmetirom |
| Lanifibranor | |
| Firsocostat | |
| Aramchol | |
| PNPLA3 gene silencing | |
| Semaglutide | |
| Tirzepatide | |
| FGF19/FGF21 analogues | |
| Inhibition of HSCs activation into matrix-producing myofibroblasts | |
| Treatments to reduce the immune response | Chemokine receptor inhibitors |
| Galectin-3 inhibitors | |
| Anti-platelet modulators | |