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. 2023 Oct 12;13(20):3183. doi: 10.3390/diagnostics13203183

Table 2.

The Red Flags Index to screen patients with suspected Crohn’s disease [31].

Parameter Multiplier
Non-healing or complex perianal fistula or abscess or perianal lesions 5
First-degree relative with confirmed inflammatory bowel disease 4
Weight loss (5% of usual body weight) in the last 3 months 3
Chronic abdominal pain (>3 months) 3
Nocturnal diarrhea 3
Mild fever in the last 3 months 2
No abdominal pain 30–45 min after meals 2
No rectal urgency 2

Every parameter is scored 0 if absent or 1 if present, and then it is multiplied by the relevant multiplier. The sum of each sub-score results in the final score. A score of ≥8 identifies a subject with a high probability of having underlying Crohn’s disease.