Table 2.

Distinguishing features of common urticaria and urticarial vasculitis [44]

Feature	Common urticaria	Urticarial vasculitis
Description	Mainly pruritic	Painful, tender, burning, and/or pruritic
Persistence	Between 8 and 24 hours	Between 24 and 72 hours
Residual effects	None	Purpura or hyperpigmentation
Predilection	• Trunk • Extremities • Face	• Trunk • Extremities • Face • Lateral borders of hands and feet
Dermographism	Common	Rare
Fixed lesions	No	Yes
Common triggers	• Viral illness • Antibiotics • Immunizations	• Infections • Autoimmune processes • Neoplastic processes • Drugs
Treatment	• Discontinue any new or unnecessary medications • Combinations of H1 and H2 antihistamines may be helpful • Systemic steroids can be helpful in severe cases	• Discontinue any new or unnecessary medications • H1 and H2 antihistamines for treatment of pruritus • NSAIDs for treatment of arthralgias • Systemic steroids with/without dapsone for treatment of moderate disease • Additional immunosuppressants, including mycophenolate mofetil, methotrexate, and cyclosporine A, for treatment of severe systemic disease