Figure 1.

Easier to make a “damager” drug in cancer. If any one of the five basic parts in a computer, namely a motherboard, a central processing unit, a graphics processing unit, a random-access memory, and a hard disk or solid-state drive, is damaged, the whole computer collapses. If any of the major organs in the human body is damaged, the life of the human ends. Likewise, if the any one of the six tumor-supporting units, as shown, is targeted and damaged by a drug, the tumor progression stops. Therefore, cancer drug makers have taken a full advantage of the philosophy from ancient Chinese Tai Chi, “四两拨千斤”, meaning “to make great accommodations with (relatively) little efforts”. Any single factor, such as an organic chemical, an antibody, a nucleotide, or a modified gene product with a delivering mechanism, could act as a damager to a tumor.