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. 2023 Sep 24;14(10):1858. doi: 10.3390/genes14101858

Table 4.

Comparison of potential needs and actually performed genetic testing shown for inflammatory non-infectious and non-inflammatory benign rheumatic disease categories. Differences between groups are tested using the chi-square test, with significance indicated if p < 0.05. After Bonferroni adjustments for multiple testing, results are shown with a local significance value of 0.006.

Inflammatory
[n (%)]
Non-Inflammatory [n (%)] p
Patients with potential need for genetic tests 1204 (77.1) 224 (24.1) <0.001
  • -

    for diagnostic purposes

656 (42.0) 0
  • -

    for prognostic purposes

358 (22.9) 0
  • -

    for therapeutic purposes

473 (30.3) 224 (24.1) <0.001
    • Disease-related
174 (36.8) 50 (22.3) <0.001
    • Comorbidity-related
354 (74.8) 182 (81.3) -
Patients with performed genetic tests 926 (59.3) 406 (43.7) <0.001
  • -

    for diagnostic purposes

883 (56.6) 403 (43.4) <0.001
  • -

    for prognostic purposes

1 (0.1) 1 (0.1)
  • -

    for therapeutic purposes

84 (5.4) 9 (1.0) <0.001
    • Disease-related
84 (100) 9 (100)
    • Comorbidity-related
0 0