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DOCK3 is comprised of key evolutionary conserved domains essential for protein-protein interactions. (A) Conserved protein domains for the largest isoform of the human DOCK3 protein (2030 amino acids, aa). These domains consist of an SH3 domain, a DHR-1 and DHR-2 domain, and a PxxP domain. (B) The human DOCK3 AlphaFold Predicted Protein Structure for DOCK3 is shown here. AlphaFold AF-Q8IZD9-F1 model is displayed here.
