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The proposed signaling pathways involved in decidual stromal cell motility are mediated by GnRH-II and EGF cotreatment. EGF acting on its receptor enhances the expression of GnRH-II and GnRH receptors. GnRH-II and EGF cotreatment regulates cell motility in human decidual stromal cells by activating Twist and N-cadherin pathways.
