Table 3.
Mean change in the variables related to sleep, intensity of atopic dermatitis, migraine, and GI disorders by study group.
| Final—Baseline DAO Group |
Final—Baseline Placebo Group |
||||
|---|---|---|---|---|---|
| Mean Change (95% CI) | p-Value | Mean Change (95% CI) | p-Value | ||
| Sleep | |||||
| Sleep quality | 0.13 (−0.42, 0.68) | 0.646 | 0.45 (−0.09, 1.00) | 0.102 | |
| Atopic dermatitis | |||||
| Dry skin | 0.13 (−0.58, 0.85) | 0.712 | −0.62 (−1.33, −0.09) | 0.086 | |
| Hives | −0.34 (−1.15, 0.48) | 0.419 | −0.97 (−1.78, −0.16) | 0.019 | |
| Eczema | 0.80 (−0.32, 1.92) | 0.161 | 0.30 (−0.83, 1.43) | 0.597 | |
| Migraine | |||||
| Migraine | −0.24 (−1.04, 0.57) | 0.562 | −0.58 (−1.38, 0.22) | 0.150 | |
| GI disorders | |||||
| Bloating | −0.34 (−0.81, 0.12) | 0.148 | −0.66 (−1.13, −0.20) | 0.005 | |
| Abdominal pain | −0.22 (−0.80, 0.35) | 0.443 | −0.39 (−0.97, 0.19) | 0.182 | |
| Burning | −0.58 (−1.24, 0.08) | 0.086 | 0.43 (−0.25, 1.10) | 0.209 | |
| Flatulence | −0.25 (−0.78, 0.29) | 0.366 | −0.60 (−1.14, 0.06) | 0.030 | |
| Bristol scale (1–7) | 0.02 (−0.40, 0.40) | 0.991 | 0.10 (−0.29, 0.50) | 0.606 |
Note: Changes in the estimated means are presented after incorporating age, BMI, and centered scores for each response variable as covariates. Changes with a negative sign signify a decrease after eight weeks of treatment.