Table 2.
Descriptive and general data from depressed patients before and after treatment.
| D | D0 (n = 15) | D1 (n = 15) | p-Value |
|---|---|---|---|
| Gender (F/M) | 7/8 | - | |
| Age (years) | 61.60 ± 10.60 | - | |
| SAAS (total) | 400.35 ± 160.41 | 370.40 ± 136.26 | 0.277 1 |
| HDRS | 24.93 ± 6.18 | 15.00 ± 4.11 | <0.001 2 |
| MMSE | 23.53 ± 4.52 | 24.80 ± 5.45 | <0.05 2 |
| FCSRT (TFR) | 27.97 ± 10.81 | 31.49 ± 10.55 | <0.01 1 |
| FCSRT (TR) | 33.91 ± 9.12 | 35.71 ± 10.90 | <0.05 1 |
| FCSRT (DFR) | 10.43 ± 3.50 | 12.13 ± 3.55 | <0.01 1 |
| FCSRT (DTR) | 12.94 ± 3.46 | 14.20 ± 2.39 | <0.01 1 |
| IGF-2 (ng/mL) | 241.29 ± 99.86 | 156.71 ± 35.64 | <0.01 |
| IGFBP-1 (ng/mL) | 10.02 ± 6.61 | 7.35 ± 4.16 | 0.258 |
| IGFBP-3 (ng/mL) | 456.49 ± 118.11 | 270.14 ± 39.86 | <0.001 |
| IGFBP-5 (ng/mL) | 84.24 ± 13.56 | 42.78 ± 6.14 | <0.001 |
| IGFBP-7 (ng/mL) | 82.36 ± 25.50 | 116.19 ± 29.85 | <0.05 |
The mean values and the standard deviations of the different variables are shown. The p-value was calculated and is shown in the fourth column, and it is reported according to the APA style; 1 The Wilcoxon matched pairs signed rank test was used. 2 Student’s t test was used. D0: patients before treatment. D1: patients after treatment. SAAS: Self-Assessment Anhedonia Scale. HDRS: Hamilton Depression Rating Scale. MMSE: Mini-Mental State Examination. FCSRT: Facilitated and Cued Selective Reminding Test. TFR: Total Free Recall. TR: Total Recall. DFR: Delayed Free Recall. DTR: Delayed Total Recall. IGF: Insulin-like growth factor. IGFBP: Insulin-like growth factor-binding protein.