Table 6.

Correlation between IGFs proteins and subjective scales in depressed patients before treatment.

Subjective Scales		IGF Plasma Proteins
		IGF-2 (ng/mL)	IGFBP-1 (ng/mL)	IGFBP-3 (ng/mL)	IGFBP-5 (ng/mL)	IGFBP-7 (ng/mL)
HDRS	r	−0.437	−0.077	−0.002	0.007	−0.447
	p	0.104	0.784	0.995	0.980	0.104
MMSE	r	−0.229	<0.000	0.714	0.670	0.155
	p	0.104	0.999	0.003	0.006	0.581
SAAS	r	−0.289	0.250	−0.064	−0.068	−0.089
	p	0.296	0.369	0.820	0.810	0.752
FCSRT_TFR	r	−0.256	−0.066	0.556	0.456	−0.077
	p	0.358	0.815	0.031	0.088	0.785
FCSRT_TR	r	−0.298	−0.034	0.754	0.672	−0.005
	p	0.28	0.904	0.001	0.006	0.985
FCSRT_DFR	r	−0.125	−0.05	0.409	0.294	0.183
	p	0.656	0.859	0.130	0.288	0.514
FCSRT_DTR	r	−0.394	−0.027	0.486	0.452	−0.013
	p	0.146	0.924	0.066	0.091	0.964

Spearman’s correlation coefficient, r: Coefficient values range from 1 to −1. Pearson’s correlation coefficient was employed when data followed a normal distribution (Shapiro–Wilk; p > 0.05). SAAS: Self-Assessment Anhedonia Scale. HDRS: Hamilton Depression Rating Scale. MMSE: Mini-Mental State Examination. FCSRT: Facilitated and Cued Selective Reminding Test. TFR: Total Free Recall. TR: Total Recall. DFR: Delayed Free Recall. DTR: Delayed Total Recall. IGF: Insulin-like growth factor. IGFBP: Insulin-like growth factor-binding protein.