Table 1.
Clinical characteristics of the 29 patients diagnosed with antithyroid drug-induced agranulocytosis (AIA) distributed according to sex.
| Total | Males | Females | |
|---|---|---|---|
| n (%) | 29 (100%) | 6 (20.6%) | 23 (79.3%) |
| Age at diagnosis of AIA (years), mean ± SD | 56.3 ± 15 | 65.0 ± 16 | 53.5 ± 14 |
| Diabetes mellitus, n (%) | 3 (10.3%) | 0 (0%) | 3 (13.0%) |
| Hypertension, n (%) | 13 (44.8%) | 3 (50%) | 10 (43.5%) |
| Active smoker, n (%) | 3 (10.3%) | 0 (0%) | 3 (13.0%) |
| Former smoker, n (%) | 4 (13.7%) | 3 (50%) | 1 (4.3%) |
| Autoimmune diseases, n (%) | 7 (24.1%) | 1(16.7%) | 6 (26.1%) |
| Graves’ disease, n (%) | 21 (72.4%) | 4 (66.7%) | 17 (73.9%) |
| Amiodarone-induced hyperthyroidism, n (%) | 7 (24.1%) | 2 (33.3%) | 5 (21.7%) |
| Hyperfunctioning multinodular goiter, n (%) | 1(3.4%) | 0 (0%) | 1(4.3%) |
| Methimazole, n (%) | 21(72.4%) | 4 (66.7%) | 17 (73.9%) |
| Carbimazole, n (%) | 6 (20.7%) | 1 (16.6%) | 5 (21.7%) |
| Propylthiouracil, n (%) | 2 (6.9%) | 1 (16.6%) | 1 (4.3%) |