Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
PKG-mediated Kv1 channel phosphorylation in photoreceptors and retinal ganglion cells. Phosphorylation of Kv1 channels because of excessive cGMP/PKG signalling can increase K+ outflow. This activates Na+/K+-ATPase in photoreceptor inner segments (IS) and in unmyelinated axon tracts of retinal ganglion cells (RGCs). High ATP consumption likely precipitates cell death. OS = outer segment, NFL = nerve fibre layer, GCL = ganglion cell layer, IPL = inner plexiform layer.
