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Two-dimensional speckle-tracking strain imaging echocardiography of a patient with ATTRwt-CM (the same patient as in Figure 2). Reduced left ventricular longitudinal strain in the middle and basal segments with relatively preserved strain in the apex (i.e., apical sparing) is observed. A bull’s eye is shown in the lower right panel (Images courtesy of Centro Hospitalar Universitário Lisboa Norte, Lisboa, Portugal).
