Table 2.

Treatment of Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM).

TREATMENT OF ATTR-CM: SUMMARY KEY POINTS
Treatment of cardiovascular symptoms, complications and comorbidities
Heart failure
Arrhythmias
Thromboembolism
Orthostatic hypotension
Correction of aortic stenosis and other valvular defects (if indicated)
Heart transplantation/other measures for advanced heart failure
Specific treatments
Transthyretin stabilizers
Transthyretin silencers
Other (possible non-genetic and genetic therapies)
Supportive therapeutic measures
Exercise & Nutrition
Vaccines
Individualized approach to physical and emotional patient’s needs