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Pharmacokinetic parameters of ATB components after oral administration of 500 mg/kg ATB (n = 5)
| Parameters | Tmax (hr) |
Cmax (ng/mL) |
AUC0–24
(hr*ng/mL) |
AUC0–∞
(hr*ng/mL) |
Half-life (hr) |
MRT0–24 (hr) |
|---|---|---|---|---|---|---|
| Matrine | 0.4 ± 0.1 | 53.8 ± 28.4 | 120.5 ± 59.4 | 123.7 ± 60.0 | 3.8 ± 2.4 | 3.6 ± 1.9 |
| Maackiain | 0.6 ± 0.4 | 0.5 ± 0.4 | 0.4 ± 0.3 | - | - | 0.6 ± 0.2 |
| Dictamine | 0.3 ± 0.1 | 0.2 ± 0.2 | 0.1 ± 0.1 | - | - | 0.4 ± 0.1 |
| Fraxinellone | - | - | - | - | - | - |
