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. 2023 Oct 14;13(10):2058. doi: 10.3390/life13102058

Table 2.

Patented formulations and botanical or chemical medications from the included studies.

Study Formulation Source Species, Concentration Quality Control Reported? (Y/N) Chemical Analysis Reported? (Y/N)
DC Nieman 2013 [35] Instaflex™ contains:
glucosamine sulfate (1500 mg)
methylsulfonyl-methane (MSM) (500 mg)
white willow bark extract (standardized to 15% salicin) (250 mg)
ginger root concentrate (50 mg)
Boswellia serrata extract (standardized to 65% boswellic acid) (125 mg)
turmeric root extract (50 mg)
cayenne 40 m H.U. (50 mg)
hyaluronic acid (4.0 mg)
Direct Digital, Charlotte, United State, North Carolina, white willow bark, 15% salicin (250 mg)
Boswellia serrata, 65% boswellic acid (125 mg)
N Y
M Evans 2020 [36] Pain Bloc-R contains (per capsule):
Vitamin D3 (as cholecalciferol) (500 IU)
Vitamin B12 (0.5 mg)
White willow bark extract (std. to 15% salicin) (Salix alba) (150 mg)
Angelica root (Angelica dahurica) (50 mg)
Acetyl L-carnitine HCl (50 mg)
Caffeine (from Green Coffee bean, Coffea arabica) (37.5 mg)
L-Theanine (37.5 mg)
BenfoPure Benfotiamine (25 mg)
Pyridoxal 5 Phosphate (17 mg)
L-Tetrahydropalmatine (25 mg)
LifeSeasons Inc., United Stated, Texas White willow bark extract (std. to 15% salicin) (Salix alba) (150 mg)
Angelica root (Angelica dahurica) (50 mg)
N Y