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. 2023 Sep 26;21(10):506. doi: 10.3390/md21100506

Figure 3.

Figure 3

Histological microphotographs of skin biopsies at 10 days after wounding: comparison of IDRT- and MCDT-treated wounds. (A) Skin wounds treated with IDRT showed an abundant cell infiltrate and a neo-epidermis (NE) in the wound border. (B) Higher magnification detail of the border with the newly formed skin (NS), developed from the granulation tissue, and the wound border, mature dermis (De). (C) Neovascularization in IDRT-treated wounds in the lower part of the dermis. (D) Skin wounds treated with MCDT showed cell infiltration in different areas of the dermis along with a neo-epidermis (NE). (E) Higher magnification detail of the border between the newly developed dermis (NS) and the mature dermis from the unwounded skin (De). (F) Presence of vessels in the dermal layer in the central area of the wound. Abbreviations: IDRT = Integra Dermal Regeneration Template, NE = Neoepidermis, NS = Neoskin, De = mature dermis. Scale bar = 200 µm.