a.a. |
Amino acid |
Aβ |
Amyloid-β peptide |
AD |
Alzheimer’s Disease |
AGD |
Argyrophilic grain disease |
ALS |
Amyotrophic lateral sclerosis |
APP |
Amyloid precursor protein |
BBB |
Blood–brain barrier |
CAA |
Cerebral amyloid angiopathy |
CBD |
Corticobasal degeneration |
CPE |
Carboxypeptidase E |
CNS |
Central nervous system |
Cryo-EM |
Cryo-electron microscopy |
CSF |
Cerebrospinal fluid |
CTR |
Calcitonin receptor |
DLB |
Dementia with Lewi bodies |
EPR |
Electron paramagnetic resonance spectroscopy |
FRET |
Förster resonance energy transfer |
FTLD |
Frontotemporal lobar degeneration |
FTLD-TDP |
TDP-43 positive frontotemporal lobar degeneration |
GCI |
Glial cytoplasmic inclusions |
GRD |
Glycine-rich domain |
GSK |
Glycogen synthase kinase |
HEK293 |
Human embryonic kidney 293 cells |
IAPP |
Islet amyloid polypeptide |
IDE |
Insulin-degrading enzyme |
LB |
Lewy bodies |
LBDs |
Lewy body diseases |
LCOs |
Luminescent conjugated oligothiophenes |
LN |
Lewy neurites |
MSA |
Multiply system atrophy |
NAC |
Non-amyloid component |
NES |
Nuclear export signal |
NFTs |
Neurofibrillary tangles |
NLS |
Nuclear localization signal |
NMR |
Nuclear Magnetic Resonance spectroscopy |
NTs |
Neuropil threads |
PAGE |
Polyacrylamide gel electrophoresis |
PART |
Primary age-related tauopathy |
PAM |
Peptidylglycine alpha-amidating monooxygenase |
PD |
Parkinson’s disease |
PDD |
Parkinson’s disease dementia |
PiD |
Pick’s Disease |
PMCA |
Protein Misfolding Cyclic Amplification technique |
PK |
Proteinase K |
PrP |
Prion protein |
PSP |
Progressive supranuclear palsy |
PTMs |
Post-translational modifications |
RAMP3 |
Receptor activity modifying protein 3 |
RBD |
RNA-binding domain |
RNP |
Ribonuclear protein |
α-Syn |
α-Synuclein |
SDS |
Sodium dodecyl sulphate |
SUMO |
Small Ubiquitin-like Modifier |
T1DM |
Type I diabetes mellitus |
T2DM |
Type II diabetes mellitus |
TDP-43 |
Transactive response DNA-binding protein of 43 kDa |
TMEM106B |
Transmembrane protein 106B |