Table 5.

Comparison of results in a systematic review (Source: own elaboration).

Author	Evaluation Method	Main Results of the Ozone Group
Solovastru	Patients evaluated on days 0, 7, 14, and 30	In the control group, there was 25% complete healing. There was a significant reduction at 7, 14, and 30 days of 34%, 59%, and 73%.
Izadi	Wagner’s classification for wounds and a ruler to measure the wound were used.	There was a complete healing of the wounds in the ozone group, with a mean time of 69.44 days.
Rosul and Patskan	The healing process was determined by the tissue presenting the wound.	At 10.17 days, thanks to the use of ozone, the pain, swelling, and hyperemia observed around the wound were reduced. Granulation was observed at 14.46 days.
Zhou	Patients were evaluated one week after treatment and then evaluated monthly until healing.	Healing was greater in the ozone group; it was 92%, and there was greater recurrence and satisfaction. No adverse effects were observed.
Wainstein	The wound area was measured thanks to a transparent grid. Infections were evaluated by bacterial cultures.	Patients who were treated with ozone had a closure rate of 81%.
Zhang	Patients were evaluated at baseline, on day 11, and on day 20. Width, length, depth, healing, infection, and need for debridement were evaluated.	In the evaluation on day 20, a reduction in the wound was observed, being greater in the ozone group. After the administration of ozone, the wounds had more collagen fibers.
Kadir	On days 0 and 21, bacterial colonies were evaluated.	There was a reduction in colonies in the ozone group. Extensive scarring was also observed in this group.