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. 2023 Oct 22;28(20):7219. doi: 10.3390/molecules28207219

Table 1.

Peeling agents used in different chemical peel types [16,17,24].

Peel Type Peel Agent Depth of Penetration
Superficial AHA—glycolic acid (30–50%), lactic acid (10–30%), mandelic acid (50%)
BHA—salicylic acid (30%)
Pyruvic acid (50%)
Resorcinol (25–50%)
Jessner solution (3–7 coats)
TCA (10–35%—1 coat)
Superficial/stratum corneum exfoliation/epidermal necrosis
Penetrates the outer layer of the skin to exfoliate gently
Medium AHA—glycolic acid (>70%)—with or without pretreatment Jessner solution
BHA—salycilic acid (>30%)
TCA (30–50%)—with or without pretreatment Jessner solution
TCA 35% + glycolic acid 70%
Medium penetrates the outer layer of the skin
Reaches the middle layer of the skin to remove damaged skin cells
Deep TCA (>50%)—pretreatment Jessner solution
Phenol 88%
Baker-Gordon phenol peel (50–55% phenol)
Deep/reticular dermal necrosis
Reaches deep into the middle layer of skin to remove damaged skin cells