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. 2023 Oct 23;28(20):7230. doi: 10.3390/molecules28207230

Table 1.

Molecular properties describing Lipinski’s rule of five predicted with SwissADME webserver (http://www.swissadme.ch/, accessed on 26 February 2023).

Compound Molecular Weight Hydrogen Bond Acceptors Hydrogen Bond Donors Consensus Log p Value Drug-Likeness
MMZ-33 363.45 4 2 4.32 Yes; 0 violation
MMZ-39 397.89 4 2 4.86 Yes; 0 violation
MMZ-45 411.49 4 2 4.86 Yes; 1 violation: MLOGP > 4.15
MMZ-140 361.43 4 1 3.79 Yes; 0 violation
MMZ-147 393.43 6 2 3.37 Yes; 0 violation
MMZ-167 377.48 4 2 4.62 Yes; 0 violation