Table 2.
Aromatase inhibitory activity of compounds 5a, 5b, and 6a–i.
| Comp. | IC50 ± SEM (µM) |
|---|---|
| 5a | >12.5 |
| 5b | >12.5 |
| 6a | 0.12 ± 0.01 |
| 6b | 0.09 ± 0.01 |
| 6c | 0.40 ± 0.04 |
| 6d | >12.5 |
| 6e | >12.5 |
| 6f | >12.5 |
| 6g | >12.5 |
| Ketoconazole | 2.6 ± 0.20 |
| Letrozole | 0.002 ± 0.0002 |
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