Table 3. Associations between folic acid use during pregnancy and postpartum depressive symptoms. Pelotas Birth Cohort, 2015.

Variables	Raw analysis (n = 3,709)		Adjusted analysis (n = 2,810)*
	PR (95%CI)	p-value	PR (95%CI)	p-value
EPDS ≥ 10
No use of folic acid	1	< 0.001	1	0.112
Use for a single trimester	0.68 (0.58–0.79)		0.96 (0.80–1.14)
Use for two or three trimesters	0.68 (0.58–0.79)		0.87 (0.72–1.04)
EPDS ≥ 13
No use of folic acid	1	< 0.001	1	0.107
Use for a single trimester	0.58 (0.46–0.72)		0.84 (0.65–1.10)
Use for two or three trimesters	0.60 (0.48–0.75)		0.80 (0.61–1.04)

95%CI: 95% confidence interval; EPDS: Edinburgh Postnatal Depression Scale.

*Adjusted analysis (Poisson Regression) for age, schooling, ethnicity, income, parity, living with a partner, support from the baby’s father, trimester of initiation of prenatal care, number of prenatal consultations, smoking during pregnancy, drinking during pregnancy, physical activity during pregnancy and depressive symptoms during pregnancy (EPDS ≥ 11).