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. 2023 Sep 6;105(21):1695–1702. doi: 10.2106/JBJS.23.00247

TABLE III.

Surgery Type and 12-Month Outcomes: Multivariable, 2-Stage Instrumental Variable Estimation Results*

Revision/Conversion Dislocation
Coefficient Standard Error P Value Coefficient Standard Error P Value
Surgery type: THA (vs. HA) −0.008 0.033 0.81 0.17 0.03 <0.001
Other key covariates
 Age, in years
  66-69 Ref. Ref.
  70-74 −0.03 0.05 0.52 −0.04 0.05 0.46
  75-79 −0.09 0.48 0.068 −0.03 0.05 0.55
  80-84 −0.18 0.05 <0.001 −0.11 0.05 0.04
  85-89 −0.20 0.05 <0.001 −0.06 0.05 0.25
  ≥90 −0.33 0.06 <0.001 −0.15 0.06 0.01
 Sex
  Female Ref. Ref.
  Male 0.11 0.02 <0.001 −0.01 0.03 0.59
 Race/ethnicity
  Non-Hispanic White Ref. Ref.
  Black/African American −0.25 0.08 0.002 −0.13 0.08 0.09
  Hispanic −0.10 0.07 0.16 0.01 0.07 0.85
  Other −0.23 0.09 0.01 −0.21 0.09 0.02
 Low-income status
  No Ref. Ref.
  Yes −0.045 0.04 0.18 0.09 0.03 0.01
 No. of comorbidities 0.02 0.004 <0.001 0.03 0.004 <0.001
 Cementation −0.23 0.03 <0.001 −0.05 0.03 0.07
 Overall facility volume of THAs −0.0003 0.0001 0.02 −0.0004 0.0001 <0.001
*

For each model, the dependent variable is a binary indicator given the value of 1 if the patient experienced the outcome (e.g., revision/conversion) and given the value of 0 otherwise. Both models also included a constant term and control for the Census region of the surgery facility, an indicator for unspecified cementation, and residuals from the first-stage (choice of surgery type) instrumental variables estimation. The estimation procedure for each outcome accounted for clustering (i.e., multiple observations within the same facility). Both models were estimated using a probabilistic probit specification to account for the nonlinear, binary nature of the dependent variables and the instrumental-variable assumption of the normality of the residuals in each estimation stage. The regression coefficients represent the adjusted marginal effect associated with a unit change in the indicator covariate, controlling for all other factors. Positive or negative coefficients indicate a higher or lower likelihood, respectively, of experiencing the outcome (e.g., revision/conversion within 12 months after the index arthroplasty surgery). Given the nonlinearity of the dependent variables, the probit regression coefficients do not represent the magnitude of the effect. To provide a sense of the magnitude of the effect of our key variable of interest, surgery type, we utilized these regression coefficients to calculate the predicted (adjusted) probability associated with each surgery type (THA versus HA) for each of the 2 outcomes, while holding all other factors constant at their actual values. These predicted probabilities are presented in the text.