Figure 3.

Effect of ethanolic extract (EtOH) and ethyl acetate (AcOEt) fractions on the virus replication process. Vero cells were infected (MOI: 0.1) with either ZIKV (A) or DENV (B) for 2 h. After that, the cells were treated with CC₂₀ of each sample and incubated for 120 h. In sequence, the supernatant was collected and submitted to TCID₅₀ measurement. Non-treatment wells (DMEM only) are defined as negative control—Mock, and 6-MMPr as a positive control drug. µM/mL describes the values of concentration. Three independent experiments expressed mean ± SD. * p < 0.05, ** p < 0.01, *** p < 0.001.