The application of biomimetic hydrogel in bone tissue. Mesoporous ceramic loaded drug particles combined with polymer hydrogel to mimic the structure of bone tissue and slow release of drugs or growth factors to repair bone tissue. Biomimetic hydrogels are used as scaffolds loaded with stem cells, growth factors, drugs, ceramic powders, or ceramic particles and repair bone tissues through enzyme, light, PH regulation, direct injection, or 3D printing. Meanwhile, it can also be embedded with microsphere slow-release bioactive substances in hydrogel scaffolds to repair bone tissues. The research is mainly applied to bone tissues such as the skull, humerus, femur, phalanges, and metacarpal bones.