Table 2.

Latin American Natural Product Databases analyzed in this work.

Database Name (Country)	Number of Compounds a	Source	General Description	References
NuBBEDB (Brazil)	2223	Plants Microorganisms Terrestrial and marine animals	Natural products of Brazilian biodiversity. Developed by the São Paulo State University and the University of São Paulo.	[68,69]
SistematX (Brazil)	9514	Plants	Database composed of secondary metabolites and developed at the Federal University of Paraiba.	[70,71]
UEFS (Brazil)	503	Plants	Natural products that have been separately published, but there is no common publication nor public database for it. Developed at the State University of Feira de Santana.	[72]
NAPRORE-CR (Costa Rica)	359	Plants Microorganisms	Developed in the CBio3 and LaToxCIA Laboratories of the University of Costa Rica.	*
LAIPNUDELSAV (El Salvador)	214	Plants	Developed by the Research Laboratory in Natural Products of the University of El Salvador.	*
UNIIQUIM (Mexico)	1112	Plants	Natural products isolated and characterized at the Institute of Chemistry of the National Autonomous University of Mexico.	[76]
BIOFACQUIM (Mexico)	553	Plants Fungus Propolis Marine animals	Natural products isolated and characterized in Mexico at the School of Chemistry of the National Autonomous University of Mexico and other Mexican institutions.	[77,78]
CIFPMA (Panama)	363	Plants	Natural products that have been tested in over twenty-five in vitro and in vivo bioassays for different therapeutic targets. Developed at the University of Panama.	[73,74]
PeruNPDB (Peru)	280	Animals Plants	Created and curated at the Catholic University of Santa Maria.	[75]

The URL of the websites where the natural product databases of Latin America are allocated is in the Supplementary Material (Table S1). ^a Number of compounds contained in each database previous to the curation process. * Actually, there is not a publication associated with the database.