Table 2.

IC₅₀ values (µM) of novel thiazolinylphenyl-piperazines (2a–c; 3a-c) observed on breast and prostate cancer cell lines.

Compd.	MCF-7	SKBR-3	MDA-MB231	LNCAP	DU-145	PC-3
2a	14.7 ± 1.9	28.17 ± 4.1	31.37 ± 5.1	67.24 ± 13.1	66.63 ± 7.3	-
2b	15.93 ± 1.8	27.58 ± 5.6	39.96 ± 9.8	48.48 ± 7.3	66.58 ± 9.4	-
2c	19.47 ± 2.3	27.65 ± 4.8	36.32 ± 7.7	31.93 ± 9.2	47.74 ± 11.7	-
3a	-	-	23.27 ± 3.4	-	-	73.3 ± 10.3
3b	-	-	34.6 ± 5.4	-	-	64.96 ± 7.4
3c	-	-	47.15 ± 6.7	-	-	32.09 ± 10.2