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Combining multiple therapies against tumors through MSN delivery of siRNAs. (A) Preparation of FePt nanoparticles and siRNA coloaded mesoporous silica nanoplatform sSFP and enhanced ferroptosis process of tumor cells by Cys depletion; (B) schematic illustration of light-triggered RNA delivery by tumor-penetrating iMSNs for siPlk1/miR-200c combination therapy.
