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. 2023 Oct 20;15(20):4448. doi: 10.3390/nu15204448

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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LEA treatment modified the expression of uncoupling proteins in the liver. (A) HFD exposure enhanced the expression of Uncopling protein 1 (Ucp1), while LEA treatment in STD-exposed animals reduced its expression; (B) LEA treatment in HFD-exposed animals increased the expression of Uncopling protein 2 (Ucp2). (C) Representative blots immunostained for each of the proteins tested. Data are presented as means ± standard error of the mean (N = 6 animals/group). * p < 0.05 versus STD-fed animals treated with vehicle; # p < 0.05, ## p < 0.01, and ### p < 0.001 versus STD-fed animals treated with LEA (two-way ANOVA).