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. 2023 Oct 13;15(10):2461. doi: 10.3390/pharmaceutics15102461

Table 1.

Summary of the Aims, Methods, and Agreement between national consensuses.

Spanish Consensus French Consensus Asian Consensus Emirates Society of Ophthalmology Consensus Italian Consensus Saudi Arabia Consensus DEX-CAT Italian Consensus
Year 2019 2020 2019 2019 2017 2020 2018
Aims Treatment guidelines and consensus for the management of DME. Treatment guidelines and consensus for the management of DME with DEX-I. Treatment guidelines and consensus for the management of DME. Treatment guidelines and consensus for the management of DME. Treatment guidelines and consensus for the management of DME with DEX-I. Treatment guidelines and consensus for the management of DME. Guidelines for dexamethasone implants in patients with diabetic macular edema undergoing cataract surgery.
Methods A group of expert retinologists
developed a consensus related to clinical management of patients with DME.
In the first meeting, the panel selected and agreed first to a list of topics related to the clinical management of DME patients
Attending to these subjects, the experts developed a list of questions.
These questions were discussed, updated literature was reviewed, and responses were agreed in different meetings held from February to October 2019 (six meetings in total).
Modified Delphi consensus:
The expert opinion gathering took place in two voting rounds based on a questionnaire drawn up by a steering committee (SC).
The participants indicated their level of agreement using a nine-point Likert scale ranging from 1 (strongly disagree) to 9 (strongly agree).
Delphi questionnaire: A total of 47 questions were developed.
An expert panel of 12 retinal specialists responded to the questionnaire at 2 separate occasions in a masked fashion.
Based on evidence taken from the literature and published trials of therapies, as well as the consensus opinion of a representative expert panel convened by the Emirates Society of Ophthalmology.
Two in-person meetings in Dubai in June 2019 and December 2019.
Delphi consensus:
The Steering Committee was composed of four experts who oversaw the preliminary review of the literature and the formulation of 30 relevant statements
A panel consisting of 40 ophthalmologists/retinal specialists from across Italy.
Eight consultant ophthalmologists participated in the consensus development and represented 7 Saudi specialized institutions: 6 from the government sector and one from the private sector. A survey composed of 10 questions regarding the use of DEX-DDS in patients with DME undergoing cataract surgery was drafted by two panelists. The results of the survey were then discussed at the meeting. Consensus was considered to be reached when all experts agreed on a statement; if a full agreement was not reached, the statement was used as the basis for discussion.
Consensus Agreement Not applicable Strong consensus was reached for a statement when more than 75% of the scores were ≥7 and the median score was ≥8. When only one of these two parameters was satisfied, the statement was considered to have obtained a good consensus. Consensus on any recommendation was considered “achieved” when 9 of the 12 panelists (75%) were in agreement. Not applicable Voting results were scored as “very much agree”, “agree”, “neither agree nor disagree”, “disagree”, and “very much disagree.”
Consensus was considered when ≥75% of respondents voted “very much agree” or “agree” with a particular statement.
Not applicable Not applicable