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VAN loading and encapsulation efficiency of M1–M4 PLGA microparticles.
| PLGA Microparticle Sample | M1 | M2 | M3 | M4 |
|---|---|---|---|---|
| Encapsulation efficiency, EE, (% w/w) | 87.8 ± 9.5 | 88.2 ± 6.5 | 78.0 ± 3.3 | 85.7 ± 9.1 |
| Drug loading, DL, (% w/w) | 17.1 ± 1.9 | 16.8 ± 1.3 | 14.5 ± 0.6 | 16.5 ± 1.7 |
| Rinsed VAN (% w/w) | 0.9 ± 0.5 | 4.6 ± 1.0 | 7.4 ± 0.9 | 1.2 ± 0.8 |
| Entrapped VAN (% w/w) | 16.2 | 12.2 | 7.1 | 15.2 |
