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. 2023 Oct 17;15(20):4397. doi: 10.3390/nu15204397

Figure 7.

Figure 7

Effect of tributyrin administration on chronic ethanol-induced recruitment of RNA POL II at the CCL2 promoter in the liver: Mice were fed either a control diet (pair-fed, PF) or ethanol (ethanol-fed; EF) (5% v/v)-containing diet. Tributyrin (TB; 2 g/kg) was orally administered to ethanol-fed mice as a preventive (EF + TB (7 + 7)) or interventional (EF + TB (7 + 3)) treatment strategy. ChIP-qPCR quantification from immunoprecipitated chromatin using an anti-RNA POL II antibody was performed. Differences are expressed as fold-over PF after normalizing for input DNA. Statistical analysis: mean ± SEM. * p < 0.05, and ** p < 0.01 compared with PF or EF via ANOVA with Bonferroni’s test (n = 5–8).