Table A3.
Erythrocytes of Cord Blood | Observational Study | Intervention Trial | ||||
---|---|---|---|---|---|---|
Historical Control | Perilla Oil Group | Fish Oil Group | ||||
Fatty Acids | n = 193 | n = 91 | n = 85 | |||
Total saturated fatty acids | 49.24 ± 0.06 | 49.84 ± 0.07 | ** | 49.99 ± 0.07 | ** | |
Total mono-unsaturated fatty acids | 16.3 ± 0.07 | 15.32 ± 0.08 | ** | 15.31 ± 0.08 | ** | |
ω-6 polyunsaturated fatty acids | ||||||
Linoleic acid (LA) | 18:2n-6 | 3.94 ± 0.04 | 4.07 ± 0.05 | 4.12 ± 0.05 | * | |
Arachidonic acid (ARA) | 20:4n-6 | 14.38 ± 0.06 | 14.5 ± 0.08 | 13.64 ± 0.10 | **,## | |
Docosapentaenoic acid n-6 (DPAn-6) | 22:5n-6 | 1.00 ± 0.01 | 1.03 ± 0.02 | 0.79 ± 0.02 | **,## | |
Total ω-6 polyunsaturated fatty acids | 24.85 ± 0.08 | 25.27 ± 0.10 | ** | 23.71 ± 0.13 | **,## | |
ω-3 polyunsaturated fatty acids | ||||||
α-Linolenic acid (ALA) | 18:3n-3 | ND | ND | ND | ||
Eicosapentaenoic acid (EPA) | 20:5n-3 | 0.33 ± 0.01 | 0.32 ± 0.01 | 0.63 ± 0.03 | **,## | |
Docosapentaenoic acid n-3 (DPAn-3) | 22:5n-3 | 0.78 ± 0.01 | 0.85 ± 0.02 | 1.36 ± 0.04 | **,## | |
Docosahexaenoic acid (DHA) | 22:6n-3 | 6.52 ± 0.06 | 6.26 ± 0.08 | * | 6.91 ± 0.07 | **,## |
Total ω-3 polyunsaturated fatty acids | 7.64 ± 0.07 | 7.43 ± 0.10 | 8.91 ± 0.12 | **,## | ||
Omega-3 Index (EPA + DHA) | 6.85 ± 0.06 | 6.58 ± 0.09 | * | 7.54 ± 0.08 | **,## | |
ARA/EPA | 47.7 ± 1.27 | 46.18 ± 1.50 | 26.43 ± 1.44 | **,## | ||
ARA/DHA | 2.24 ± 0.02 | 2.36 ± 0.04 | * | 2.00 ± 0.03 | **,## | |
ω-6/ω-3 | 3.32 ± 0.04 | 3.47 ± 0.06 | 2.72 ± 0.05 | **,## |
% of total fatty acids; data are presented as means ± SEM; p-value: one-way analysis of variance followed by Tukey’s test; * p < 0.05, ** p < 0.01 vs. historical control; ## p < 0.01 vs. perilla oil.