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. 2023 Oct 17;15(10):2480. doi: 10.3390/pharmaceutics15102480

Figure 5.

Figure 5

TME-responsive hypoxia relief in tri-modal synergistic PDT/PTT/chemotherapy. (A) Schematic illustration of the synthesis of multifunctional BPN/MnO2/DOX nanocomposites and the systemic delivery of BPN/MnO2/DOX as a versatile theranostic platform for MRI-guided multifunctional therapy. Adapted with permission from ref. [82]. (B) Schematic illustration of preparing Ini@PM-HP NPs and their applications in combinational tumor treatment. Adapted with permission from ref. [84].