The effects of inhibitors on proteinases produced by M. anisopliae in medium containing cockroach cuticle. Experiments were carried out with cultures buffered at pH 3, 4, 5, 6, 7, or 8 (top axis). Shown are proteinases produced at pHs 3 and 4 without inhibitors (A) and gels incubated with pepstatin (B), phosphoramidon (C), and leupeptin (D).