Table 8.

Margin of safety calculation for butylmethoxydibenzoylmethane.

Parameter	Value
Amount of product applied daily (SCCS/1628/21 Table 3A)	24.14 mg/kg bw/day
Ingredient Concentration in finished product	2%
Typical body weight of human (bw)	60 kg
Absorption of active ingredient (DAp) (dermal absorption not known, considered as 50%)	50%
Systemic exposure dose (SED)	0.2414 mg/kg bw/day
NOAEL (considering sub chronic oral repeated dose toxicity study, rats)	450 mg/kg bw/day
MoS	NOAEL/SED = 932