Intercept |
0.72 |
0.11 |
6.30 |
< 0.0001 |
0.50-0.95 |
MR effect size (In) |
0.30 |
0.11 |
2.75 |
0.006 |
0.09-0.52 |
Taxa (mammal) |
0.07 |
0.23 |
0.33 |
0.74 |
-0.38-0.54 |
MR : Taxa |
0.16 |
0.22 |
0.71 |
0.48 |
-0.28-0.59 |
Variance components: outer factor: Lab (N=16), inner factor: Study. ID (N=21). tau^2- Estimate = 0.00, sqrt = 0.09 |
|
|
|
|
|
Residual heterogeneity: QE(df=31)=27.47,p=0.65 |
|
|
|
|
|
Test of moderators: QM(df=3)=9.53,p=0.023 |
|
|
|
|
|
(b) |
Estimate |
s.e. |
z |
P |
95% C.I. |
Intercept |
0.77 |
0.10 |
7.69 |
< 0.0001 |
0.57-0.96 |
MR effect size (ln) |
0.32 |
0.11 |
3.00 |
0.002 |
0.11-0.54 |
Before / after effect (yes) |
-0.30 |
0.38 |
-0.79 |
0.43 |
-1.06-0.45 |
MR : Time effect |
-0.00 |
0.31 |
0.05 |
0.96 |
-0.59-0.62 |
Variance components: Lab (N=16), inner factor: Study.ID (N=21). tau^2 - Estimate = 0.03, sqrt = 0.16 |
|
|
|
|
|
Residual heterogeneity: QE(df=31)=27.72,p=0.64 |
|
|
|
|
|
Test of moderators: QM(df=3)=9.39,p=0.024 |
|
|
|
|
|
(c) |
Estimate |
s.e. |
z |
P |
95% C.I. |
Intercept |
0.76 |
0.10 |
7.51 |
< 0.0001 |
0.56-0.96 |
MR effect size (ln) |
0.32 |
0.11 |
2.97 |
0.003 |
0.11-0.52 |
Exp./ control effect (yes) |
0.08 |
0.31 |
0.25 |
0.80 |
-0.53-0.69 |
MR : Exp. / control effect |
-0.05 |
0.32 |
-0.00 |
0.99 |
-0.62-0.62 |
Variance components: Lab (N=16), inner factor: Study.ID (N=21). tau^2- Estimate = 0.02, sqrt = 0.15 |
|
|
|
|
|
Residual heterogeneity: QE(df=31)=28.18,p=0.61 |
|
|
|
|
|
Test of moderators: QM(df=3)=8.88,p=0.030 |
|
|
|
|
|
(d) |
Estimate |
s.e. |
|
P |
95% C.I. |
Intercept |
0.76 |
0.11 |
7.12 |
< 0.0001 |
0.55-0.97 |
MR effect size (ln) |
0.34 |
0.11 |
3.00 |
0.003 |
0.12-0.56 |
Met. variable (HR) |
0.15 |
0.22 |
0.68 |
0.49 |
-0.28-0.59 |
MR : Met. variable |
0.01 |
0.23 |
0.06 |
0.96 |
-0.43-0.46 |
Variance components: outer factor: Lab (N=16), inner factor: Study.ID (N=21). tau^2- Estimate = 0.03, sqrt = 0.16 |
|
|
|
|
|
Residual heterogeneity: QE(df=31)=28.03,p=0.62 |
|
|
|
|
|
Test of moderators: QM(df=3)=9.21,p=0.027 |
|
|
|
|
|
e) |
Estimate |
s.e. |
z |
P |
95% C.I. |
Intercept |
0.82 |
0.20 |
4.09 |
< 0.0001 |
0.43-1.21 |
MR effect size (In) |
0.26 |
0.20 |
1.30 |
0.19 |
-0.13-0.64 |
Treat. Type 2 |
0.01 |
0.29 |
0.02 |
0.98 |
-0.57-0.58 |
Treat. Type 3 |
-0.20 |
0.32 |
-0.62 |
0.53 |
-0.81-0.42 |
MR: Treat. Type 2 |
0.09 |
0.27 |
0.34 |
0.74 |
-0.44-0.62 |
MR: Treat. Type 3 |
0.08 |
0.29 |
0.28 |
0.78 |
-0.49-0.66 |
Variance components: Lab (N=16), inner factor: Study.ID (N=21). tau^2- Estimate = 0.04, sqrt = 0.20 |
|
|
|
|
|
Residual heterogeneity: QE(df=29)=27.77,p=0.53 |
|
|
|
|
|
Test of moderators: QM(df=5)=9.32,p=0.097 |
|
|
|
|
|