Fig. 5.

The effect of delay for treating infections on the epidemic outbreak and the average level of resistance when the therapeutic treatment is successful. Line 1 The treatment rate $q^T=0.5$. A The average resistance level $\eta$ of the host population for $\theta \in \{0.5,1\}$. C, E The between-host dynamics for $\theta =0.5$ and 1, where ${\mathcal{R}}_0=0.3922$ and 2.6750 respectively. Line 2 As in line 1 for $q^T=0.9$ where ${\mathcal{R}}_0=0.1120$ and 0.5685 respectively. Other parameter values are $({\sigma }_0,m_0,k_0,p_1/p_0,k_1/k_0,\mu )=(0.05,0.05,20,0.5,0.3,0.8598)$ and $\mathrm{\Lambda }=5\text{e}4$, ${\mu }_h=5.2675\text{e}-2$, ${\beta }_0=1.2\text{e}-3$, ${\alpha }_0=7.5\text{e}-2$, $r_0=9\text{e}3$