Table 2.
Baseline characteristics according to tertiles of the TyG index
| T1 TyG < 8.633 (n = 1509) |
T2 TyG [8.633,9.096) (n = 1509) |
T3 TyG ≥ 9.096 (n = 1512) |
P value | |
|---|---|---|---|---|
| Age, years | 60.26 ± 10.10 | 59.78 ± 10.08 | 58.57 ± 9.80 | < 0.001 |
| Male | 1215 (80.5) | 1169 (77.5) | 1141 (75.5) | 0.003 |
| BMI, kg/m2 | 25.07 ± 3.12 | 26.04 ± 3.13 | 26.55 ± 3.10 | < 0.001 |
| DM | 358 (23.7) | 611 (40.5) | 982 (64.9) | < 0.001 |
| Hypertension | 858 (56.9) | 971 (64.3) | 1037 (68.6) | < 0.001 |
| SBP, mmHg | 129.64 ± 17.78 | 130.99 ± 17.54 | 130.95 ± 17.64 | 0.058 |
| DBP, mmHg | 76.54 ± 10.71 | 77.43 ± 11.01 | 77.87 ± 11.04 | 0.003 |
| Current smoker | 467 (30.9) | 471 (31.2) | 509 (33.7) | 0.210 |
| ACS | 904 (59.9) | 965 (63.9) | 944 (62.4) | 0.069 |
| Family history of CAD | 176 (11.7) | 184 (12.2) | 202 (13.4) | 0.351 |
| Previous MI | 335 (22.2) | 354 (23.5) | 346 (22.9) | 0.712 |
| Previous PCI | 290 (19.2) | 284 (18.8) | 322 (21.3) | 0.186 |
| Previous CABG | 20 (1.3) | 18 (1.2) | 14 (0.9) | 0.576 |
| Previous stroke | 201 (13.3) | 173 (11.5) | 208 (13.8) | 0.136 |
| Previous PAD | 103 (6.8) | 77 (5.1) | 80 (5.3) | 0.083 |
| CKD | 18 (1.2) | 29 (1.9) | 43 (2.8) | 0.005 |
| LVEF, % | 62.68 ± 4.90 | 62.41 ± 5.44 | 62.59 ± 4.97 | 0.338 |
| Laboratory results | ||||
| TyG | 8.30 ± 0.25 | 8.86 ± 0.14 | 9.53 ± 0.36 | < 0.001 |
| FBG, mmol/L | 5.34 ± 0.95 | 6.07 ± 1.43 | 7.96 ± 3.09 | < 0.001 |
| HbA1c, % | 5.96 ± 0.80 | 6.28 ± 0.97 | 7.03 ± 1.48 | < 0.001 |
| TC, mmol/L | 3.68 ± 0.92 | 4.02 ± 0.98 | 4.32 ± 1.08 | < 0.001 |
| TG, mmol/L | 0.99 ± 0.24 | 1.53 ± 0.34 | 2.45 ± 0.86 | < 0.001 |
| LDL-C, mmol/L | 2.18 ± 0.80 | 2.48 ± 0.86 | 2.58 ± 0.94 | < 0.001 |
| HDL-C, mmol/L | 1.21 ± 0.33 | 1.10 ± 0.28 | 1.01 ± 0.25 | < 0.001 |
| hsCRP, mg/L | 2.32 ± 2.95 | 2.79 ± 3.21 | 2.89 ± 3.01 | < 0.001 |
| Creatinine, µmol/L | 81.00 ± 15.77 | 83.04 ± 17.20 | 84.70 ± 28.13 | < 0.001 |
| Lipoprotein(a), mg/L | 32.49 ± 31.10 | 30.35 ± 30.34 | 28.42 ± 30.37 | 0.001 |
| Medications | ||||
| Clopidogrel | 1298 (86.0) | 1277 (84.6) | 1285 (85.0) | 0.536 |
| ACEI/ARB | 371 (24.6) | 385 (25.5) | 414 (27.4) | 0.202 |
| β-blocker | 1288 (85.4) | 1340 (88.8) | 1366 (90.3) | < 0.001 |
| CCB | 511 (33.9) | 547 (36.2) | 576 (38.1) | 0.052 |
| Statins | 1457 (96.6) | 1456 (96.5) | 1470 (97.2) | 0.452 |
| Antidiabetic drugs | 308 (20.4) | 460 (30.5) | 746 (49.3) | < 0.001 |
| Nitrate | 1457 (96.6) | 1459 (96.7) | 1475 (97.6) | 0.224 |
| Angiographic findings | ||||
| SYNTAX score | 15.29 ± 5.58 | 15.55 ± 5.78 | 15.74 ± 5.92 | 0.078 |
| Left main disease | 165 (10.9) | 183 (12.1) | 184 (12.2) | 0.489 |
| three-vessel disease | 585 (38.8) | 608 (40.3) | 677 (44.8) | 0.002 |
| Chronic total occlusion | 123 (8.2) | 125 (8.3) | 144 (9.5) | 0.334 |
| Type B2/C lesion | 1269 (84.1) | 1259 (83.4) | 1283 (84.9) | 0.564 |
| Ostial lesions | 363 (24.1) | 357 (23.7) | 340 (22.5) | 0.571 |
| Thrombotic lesions | 15 (1.0) | 18 (1.2) | 26 (1.7) | 0.192 |
| Severe calcification | 60 (4.0) | 44 (2.9) | 49 (3.2) | 0.255 |
Values are presented as mean ± standard deviation or number (%) and comparison among groups was achieved by One-way ANOVA, Chi-square test or Fisher’s exact test as appropriate. Abbreviations as in Table 1