Table 1.
Demographic and prehospital data stratified according to survival status after 365 days
| Total population | Survivors at 365 days | Deceased at 365 days | p-value | |
|---|---|---|---|---|
| n = 565 | n = 470 (65%) | n = 248 (35%) | ||
| Demography | ||||
| Age—year (± SD) | 62 ± 13 | 60 ± 14 | 67 ± 12 | < 0.0001 |
| Male gender—n (%) | 458 (81%) | 305 (82%) | 153 (79%) | 0.34 |
| Randomization allocation | ||||
| MAP at 63 mmHg—n (%) | 279 (51%) | 185 (51%) | 94 (49%) | 0.69 |
| PaO2 at 9–10 kPa—n (%) | 284 (50%) | 191 (51%) | 93 (48%) | 0.48 |
| Cardiac arrest characteristics | ||||
| Witnessed arrest—n (%) | 466 (85%) | 314 (87%) | 152 (80%) | 0.03 |
| Bystander CPR—n (%) | 501 (88%) | 343 (92%) | 158 (81%) | < 0.0001 |
| Bystander defibrillation—n (%) | 125 (23%) | 90 (24%) | 35 (19%) | 0.09 |
| Shockable primary rhythm—n (%) | 460 (84%) | 312 (87%) | 148 (76%) | 0.0001 |
| Time to ROSC—min. (Q1–Q3) | 18 (12–26) | 15 (10–20) | 25 (17–33) | < 0.0001 |
| Lactate at admission—mmol/L. (Q1-Q3) | 5 (2.9–7.7) | 3.9 (2.3–6.8) | 6.0 (4.1–9.4) | < 0.0001 |
| Acute CAG | 513 (91%) | 331 (89%) | 182 (94%) | 0.09 |
| PCI—n (%) | 229 (41%) | 149 (40%) | 80 (41%) | 0.80 |
| LVEF at hospital admission | 35 ± 14 | 37 ± 14 | 34 ± 14 | 0.03 |
| Pre-arrest comorbidities | ||||
| Previous AMI—n (%) | 121 (21%) | 73 (20%) | 48 (25%) | 0.09 |
| Congestive heart failure—n (%) | 105 (19%) | 51 (15%) | 54 (28%) | 0.004 |
| Hypertension—n (%) | 272 (48%) | 164 (44%) | 108 (56%) | 0.009 |
| Previous TCI/stroke—n (%) | 41 (7%) | 24 (7%) | 17 (9%) | 0.28 |
| Diabetes—n (%) | 80 (14%) | 41 (11%) | 349(20%) | 0.003 |
| Chronic obstructive pulmonary disease—n (%) | 46 (8%) | 21 (6%) | 25 (13%) | 0.01 |
| Chronic kidney disease—n (%) | 24 (4%) | 14 (4%) | 10 (6%) | 0.19 |
| Atrial fibrillation—n (%) | 99 (18%) | 49 (13%) | 50 (25%) | 0.0002 |
| Time intervals | ||||
| Time from arrest to ICU admission—h (q1–q3) | 2.4 (1.9–3.1) | 2.4 (1.9–3.1) | 2.5 (1.9–3.1) | 0.46 |
| Time from arrest to PAC insertion—h (q1–q3) | 3.0 (2.0–3.0) | 3.0 (2.0–3.0) | 3.0 (2.0–3.0) | 0.63 |
CAG, coronary angiography; CPR, cardiopulmonary resuscitation; Q1–Q3, interquartile range; LVEF, left ventricular ejection fraction; n, number; PCI, percutaneous coronary intervention; ROSC, return of spontaneous circulation; SD, standard deviation; TCI, transitory cerebral ischemia; MAP, mean arterial blood pressure; PaO2, partial pressure of oxygen in arterial blood; kPa, kilo pascal. Bold indicates statistical significance which is a p-value below 0.05