Thiazide drug	Dose range	Number of trials	Total patients randomized	N (% males) and N (% females)	Mean duration (weeks)	Mean age (years)	Baseline systolic/diastolic blood pressure mmHg
Bendrofluazide	1.25 to 10.0 mg/day	1	257	103 (40%) 154 (60%)	12 weeks	57 years	165/102 mmHg
Chlorthalidone	12.5 to 100 mg/day	8*	1265	581 (50.4%) 684 (49.6%)	7 weeks	53 years	163/88 mmHg
Cyclopenthiazide	0.05 to 0.50 mg/day	1	53	22 (41.5%) 31 (49.6%)	8 weeks	57 years	164/97 mmHg
Hydrochlorothiazide	3 to 100 mg/day	40	7560	4152 (57%) 3408 (43%)	8 weeks	54 years	155/100 mmHg
Indapamide	1 to 5 mg/day	10	2075	1018 (48.4%) 1057 (51.6%)	10 weeks	58 years	161/98 mmHg
Metolazone	0.5 to 2.0 mg/day	1	105	46 (43.8%) 59 (56.2%)	6 weeks	Not reported	150/98 mmHg
Overall		60 trials	11,282*	5922 (53.0%) 5360 (47.0%)	8 weeks	55 years	158/99 mmHg