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. 2014 May 29;2014(5):CD003824. doi: 10.1002/14651858.CD003824.pub2
Drug and dose range Number of trials
reporting data
MD (95% CI)
µmol/L
Bendrofluazide 1.25 to 10.0 mg/day 1 46.6 (33.2to 59.9)
Cyclopenthiazide 0.05 to 0.5 mg/day 1 19.5 (‐36.2 to 75.3)
Chlorthalidone 12.5 to 100 mg/day 2 64.2 (45.7 to 82.6)
Hydrochlorothiazide 3 to 100 mg/day 5 32.9 (26.1 to 39.7)
Indapamide 1 to 5 mg/day 4 39.8 (33.5 to 46.1)
Overall^ 13 38.2 (34.2 to 42.2)